生命早期阶段影响以后的养行为和生理学在轻生小猪
E Huenul1, S M Martin-Orùe1, L Fabà2
1Animal Nutrition and Welfare Service (SNIBA), Department of Animal and Food Science, Autonomous University of Barcelona, Bellaterra, 08193, Spain.
Journal of animal science
|December 19, 2025
概括
早期生长率显著影响低出生体重 (LBW) 的小猪.
科学领域:
- 动物科学动物科学
- 生理学 生理学 生理学
- 代谢过程中的代谢.
背景情况:
- 低出生体重 (LBW) 的小猪面临着发育方面的挑战.
- 早期的生活经历可以对小猪的发育产生长期影响.
- 了解生长速度的影响对于改善小猪的结果至关重要.
研究的目的:
- 研究早期生长速度对LBW小猪的新陈代谢和养行为的印记效应.
- 分析与生长性能相关的生理生物标志物和内基因表达.
- 为了将早期生长模式与断奶后的行为联系起来.
主要方法:
- 使用了2x2的因数设计,根据哺乳和托儿所生长率,使用了46个体重小猪.
- 测量平均每日收益,体重和断奶后的养行为.
- 分析了血液和尿液的生物标志物,并在58天的年龄时测定了头基因表达.
主要成果:
- 缓慢生长的小猪在断奶后的食器上花费的时间更少.
- 缓慢哺乳的猪仔表现出改变的血液 (较低的Zn,GABA) 和尿液 (较高的尿素,金氨酸,氨酸) 资料.
- 缓慢培养的小猪表现出血中Zn的低值和尿液的变化 (KYN/肌素的升高) 形状,并增加了状免疫基因表达 (CXCL2).
结论:
- 生命早期的生长率,特别是在哺乳期,显著影响LBW小猪的新陈代谢和行为.
- 哺乳期和幼儿园期的影响可以独立,突出关键的发育窗口.
- 这些发现表明,早期生长印记会影响小猪的整体表现和生理状态.
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