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Updated: Jan 8, 2026

Application of CRISPR Interference CRISPRi for Gene Silencing in Pathogenic Species of Leptospira
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Published on: August 14, 2021

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类型I-Fv和工程类型IV-A1的CRISPR-Cas效应器促进了大肠杆菌的基因组缩小

Nathalie Klein1, Mariana Sanchez-Londono1, Meral M Kara1

  • 1Department of Biology, Philipps-Universität Marburg, Hans-Meerwein-Straße 6, 35043 Marburg, Germany.

Nucleic acids research
|December 19, 2025
PubMed
概括

我们开发了新的CRISPR-Cas基因组编辑工具,用于大型DNA删除. 这些系统源自I型和IV型-A型CRISPR系统,为研究DNA修复机制提供了新的途径.

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