相关实验视频

Updated: May 7, 2026

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species

Published on: February 27, 2018

纠正"因与亨廷顿病相关的LIG1 K845N变体损害了识别和结效率"

NAR molecular medicine

|December 19, 2025

概括

此更正更新了之前发表的一篇文章的数字物体标识符 (DOI). 修正后的DOI确保了科学研究内容的准确引用和检索.

科学领域:

科学出版业的科学出版.
学术传播学术交流

背景情况:

准确的引用对于科学完整性至关重要.
数字物体识别器 (DOI) 对于定位研究至关重要.

研究的目的:

为特定的科学文章提供正确的DOI.
确保研究人员能够访问预期的出版物.

主要方法:

识别错误的DOI. 错误的DOI.
与出版商一起验证和更新DOI.

主要成果:

这篇文章的DOI已被修正为10.1093/nar/ugaf038.
这确保了正确的引用和可访问性.

结论:

准确的元数据对于科学发现的传播至关重要.
校正促进了可靠的学术交流.

更多相关视频

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System

Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System

Published on: December 10, 2021

相关概念视频

Huntington Disease l: Introduction

Huntington Disease l: Introduction

Huntington disease or HD is a progressive, fatal neurodegenerative disorder inherited in an autosomal dominant pattern.PathophysiologyIt is caused by expansion of the CAG trinucleotide repeat in the HTT gene on chromosome 4 (4p16.3), producing an abnormal huntingtin protein with an expanded polyglutamine tract. This misfolded protein disrupts cellular function, leading to neuronal death. Normal alleles have ≤26 repeats, 27–35 are intermediate (risk of expansion), 36–39 show reduced penetrance,...