泌尿病学实践中的IgG4相关疾病:错误恶性瘤的案例系列
Mounish Nuthalapati1, Arun Ramdas Menon2, Rohan Rajendran1
1Department of Urology and Renal Transplant, Amrita Institute of Medical Sciences, Kochi, Kerala India.
Indian journal of surgical oncology
|December 19, 2025
概括
与免疫球蛋白G4相关的疾病 (IgG4-RD) 可以影响尿路,经常模仿癌症. 早期活检和多学科评估是准确诊断和避免不必要的手术的关键.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 腎臟病學 (nephrology) 是一種醫學.
- 类风湿病学 类风湿病学
- 病理学 病理学 病理学
背景情况:
- 免疫球蛋白G4相关疾病 (IgG4-RD) 是一种罕见的全身纤维炎症疾病.
- IgG4-RD通常会影响胰腺等器官,但也可能涉及泌尿道,带来诊断挑战.
- 在IgG4-RD中的Tumefactive病变可以模仿恶性瘤,导致误诊和积极的治疗.
研究的目的:
- 报告四名患有涉及尿路的IgG4-RD的患者的临床表现,诊断挑战和管理情况.
- 突出早期怀疑和准确诊断在尿路IgG4-RD管理中的重要性.
- 强调在复杂案件中多学科讨论的作用.
主要方法:
- 回顾四名被诊断患有影响尿路的IgG4-RD的患者.
- 分析临床表现,成像检测结果,手术干预和组织病理学结果.
- 多学科团队会议用于案例讨论和管理规划.
主要成果:
- 尿路IgG4-RD的四例病例呈现出脏盆腔质量,上腺质量和上腺质量导致水尿基缩.
- 最初的成像显示所有病例都存在恶性瘤,导致nephroureterectomy,nephrectomy或部分nephrectomy.
- 组织病理学评估证实了IgG4-RD,强调了恶性瘤的诊断模仿.
结论:
- 尿路IgG4-RD不常见,并且经常模仿恶性瘤,造成诊断困境.
- 至少侵入性活检用于组织诊断和多学科评估对于准确的诊断至关重要.
- 早期怀疑和及时诊断可以防止对IgG4-RD进行不必要的激进手术.
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