在INDEPSO-ISPSM关于腹恶性瘤的共识 - 状尾瘤和 Pseudomyxoma Peritonei
Vivekanand Sharma1, Somashekhar Sp2, Rohit Kumar2
1Dept of Colorectal Surgery, East Suffolk and North Essex NHS Foundation, Ipswich, UK.
Indian journal of surgical oncology
|December 19, 2025
概括
这项共识实践为管理罕见的粘膜尾瘤 (MANs) 和假膜瘤 (PMP) 提供了建议. 对于特定的高级MAN和PMP病例,建议使用高热性腹腔内化学疗法 (CRS-HIPEC) 进行细胞还原性手术.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 在瘤学瘤学.
背景情况:
- 粘菌性尾瘤 (MANs) 和假膜瘤 (PMP) 呈现出独特而罕见的治疗挑战.
- 现有的国际指导方针可能无法完全解决这些疾病的所有临床情景.
研究的目的:
- 在MAN和PMP管理中建立专家共识,以解决临床相关问题.
- 加强和更新现有国际指南中的建议.
主要方法:
- 一种经过修改的Delphi方法,由45名国际小组成员进行两轮投票.
- 回答了42个问题,涵盖了MAN和PMP管理中的七个关键问题.
- 共识被定义为>70%的协议,强大的共识>90%.
主要成果:
- 在42个问题中有36个问题 (88%) 达成了共识.
- 推CRS-HIPEC用于穿孔 (pT4) 高度MAN,pT4差异化/无腹膜疾病的标记环细胞瘤以及所有明显腹膜疾病.
- 除了CRS,还建议HIPEC用于PMP;对于pT3 HAMN或经外科手术检测到的腹传播的MAN,没有达成共识.
结论:
- 专家的共识支持CRS-HIPEC针对特定的高级MAN和PMP,与国际准则保持一致,但也进行了改进.
- 该共识提供了关于可争议的干预措施的指导,如生育节约手术和额外外皮质疾病的CRS.
- 建议在尾切除术后的场景中对预防性CRS和HIPEC采取更严格的方法.
更多相关视频
07:20Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
Published on: December 21, 2012
16.4K
08:51Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
10.6K
相关概念视频
01:22Appendicitis-I: Introduction
2.1K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
2.1K
01:29Appendicitis-II: Diagnostic Studies and Management
461
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
461