系统性审查的报告和方法质量,以支腰部疼痛临床实践指南:一项超流行病学研究
Adam Khan1, Will Roberts2, Landon Frank3
1Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, United States.
Frontiers in pain research (Lausanne, Switzerland)
|December 19, 2025
概括
系统性审查 (SRs) 支持腰部疼痛 (LBP) 临床指南的质量有所变化. 科克兰审查比非科克兰审查得分更高,但报告和方法的改进是必要的,以获得更强有力的证据.
科学领域:
- 肌肉骨系统疾病 肌肉骨系统疾病
- 基于证据的医学基于证据的医学.
- 卫生研究方法论 卫生研究方法论
背景情况:
- 腰部疼痛 (LBP) 是一个全球性的健康问题,导致严重的残疾和经济负担.
- 临床实践指南 (CPG) 对于LBP严重依赖系统性审查 (SRs) 来提供建议.
- 在LBP CPG中使用的SR的报告和方法严谨性需要进行彻底的评估.
研究的目的:
- 进行LBP CPG中引用的SR的元流行病学评估.
- 评估这些SRs的报告和方法质量.
- 为了比较Cochrane与非CochraneSRs的质量.
主要方法:
- 采用了一个横截面的元流行病学研究设计.
- 在2017-2021年期间公布的确定LBP CPG和提取的支持SRs.
- 使用PRISMA评估报告质量,使用AMSTAR-2标准评估方法质量.
主要成果:
- 在八个LBP CPG中确定了90个独特的SR.
- SRs表现出对PRISMA (平均83%) 和AMSTAR-2 (平均79.3%) 标准的多样性,在协议注册和偏差评估方面存在共同的缺陷.
- 与非Cochrane SR相比,Cochrane SR表现出明显更高的报告 (PRISMA) 和方法 (AMSTAR-2) 质量.
结论:
- 支持LBP CPG的SRs表现出不一致的报告和方法质量,在关键领域存在明显的差距.
- 科克莱恩SR通常在质量上优于非科克莱恩SR,但在证据基础中占比较小.
- 通过协议注册,PRISMA遵守,排除研究的透明报告和偏见评估来加强SR,对于加强LBP指南至关重要.
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