相关实验视频
Updated: Jan 7, 2026

05:44
Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
Published on: June 10, 2025
790
来自皮肤病学大师班2025年会议:皮肤病学家对皮肤性和全身性狼的实用方法
Beth Childs1, Joseph F Merola1
1Dr. Merola and Ms. Childs are with the Department of Dermatology, Department of Medicine, and Division of Rheumatology at UT Southwestern Medical Center in Dallas, Texas.
The Journal of clinical and aesthetic dermatology
|December 19, 2025
概括
皮肤科医生可以通过查皮肤性红斑狼 (CLE) 患者来早期检测全身性红斑狼 (SLE). 不同的CLE亚型表明SLE进展的风险不同,指导风险分层和管理.
科学领域:
- 皮肤病学 皮肤病学
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 皮肤性红斑狼 (CLE) 可能是系统性红斑狼 (SLE) 的早期迹象,在近三分之一的病例中存在.
- 皮肤科医生通过对CLE患者进行适当的查,在早期发现全身性疾病方面发挥着至关重要的作用.
- 慢性CLE亚型对系统性进展有不同的风险:急性CLE与活跃的SLE有关,亚急性CLE具有中等风险,慢性CLE通常受皮肤限制.
研究的目的:
- 为CLE患者的风险分层,查和共同管理提供一个以皮肤学为重点的框架.
- 引入"LABS FOR"的SLE记忆法,以指导实验室评估.
- 为了在CLE中呈现一个更新的视觉算法,用于查和监测实践.
主要方法:
- 综合基于证据和专家的建议,对血清学,人口学,临床和遗传预测系统性参与的预测因素.
- 审查2019年美国风湿病学院/欧洲反风湿病联盟 (ACR/EULAR) 的分类标准.
- 突出适当的抗核抗体 (ANA) 测试,症状审查和针对性的二线实验室测试.
主要成果:
- 对CLE的结构化方法可以改善SLE的早期检测和管理.
- 在系统性疾病的实验室评估中,SLE的"LABS FOR"记忆力辅助.
- 一个更新的算法为CLE患者的查和监测实践提供了指导.
结论:
- 皮肤科医生在识别需要系统评估的CLE患者方面是至关重要的.
- 实施CLE知情的系统查方法可以提高狼谱的患者的治疗结果.
- 与风湿病学合作管理对于全面的患者护理至关重要.
相关概念视频
Skin Diseases and Disorders
5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
Changes in Skin Color: Clinical Perspectives
3.2K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.2K
Skin Cancer
5.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.7K
Confocal Fluorescence Microscopy
19.8K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
19.8K
Autoimmune Disorders
1.4K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
1.4K
Introduction to the Integumentary System
12.8K
The integumentary system is the organ system that comprises the skin and its associated structures. It is the largest system in the human body and plays a crucial role in protecting and maintaining homeostasis. The integumentary system serves several functions including protection, regulation, sensation, and secretion.
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...
12.8K

