在手和手腕病理方面使用类固醇注射
Rosemary J Bell1,2, Rebecca Cervenak3, Molly I Flint4
1Medical Education, University of Queensland, Brisbane, AUS.
Cureus
|December 19, 2025
概括
皮质类固醇注射对于手和手腕疼痛很常见,但缺乏明确的指导方针. 虽然通常是安全的,但存在罕见的严重并发症,需要进一步研究以获得最佳使用.
科学领域:
- 整形外科 整形外科 整形外科
- 类风湿病学 类风湿病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 皮质类固醇注射经常用于手和手腕病理,这些病理对保守治疗没有反应.
- 目前关于在手和手腕疾病中使用皮质类固醇的指导方针是有限的.
- 关于疗效和安全性的证据是可变的,通常从较大的关节中推断出来.
研究的目的:
- 审查当前在手和手腕病理中使用皮质类固醇的实践.
- 检查关于皮质类固醇注射的有效性和安全性的现有证据.
- 将当前的证据与现有的英国和美国指南进行比较.
主要方法:
- 对PubMed和Cochrane数据库进行了全面的文献审查.
- 包括涉及使用皮质类固醇治疗常见成人手部疾病的研究.
- 提取和分析了有关剂量,时间,副作用和并发症的数据.
主要成果:
- 在手和手腕内注射皮质类固醇通常被认为是安全的,严重的副作用不常见.
- 报道了一些严重并发症的孤立病例,如死角性炎和曲肌破裂.
- 建议的最大剂量包括每年四次注射,每隔三个月,建议使用贝他美沙或甲基前尼索隆,但基于证据薄弱.
结论:
- 对手和手腕病理的皮质类固醇使用很普遍,但缺乏坚实的,基于证据的指导方针.
- 最佳剂量,时间,疗效和安全性需要进一步研究.
- 有针对性的研究对于建立清晰的,基于证据的治疗方案来治疗这些疾病至关重要.
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