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Updated: Jan 8, 2026

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Published on: September 8, 2012

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在III-A型CRISPR-Cas反应期间,CARF-HAD酸酶效应剂提供免疫力

Gianna Stella1,2, Linzhi Ye2,3, Sean F Brady3

  • 1Laboratory of Bacteriology, The Rockefeller University, New York, NY 10065, United States.

Nucleic acids research
|December 19, 2025
PubMed
概括

研究人员确定了与CRISPR相关的HAD酸酶 (Chp) 蛋白质,这些蛋白质可以保护细菌免受菌体感染. Chp蛋白激活免疫反应,通过耗尽必要的细胞分子来阻止病毒的传播.

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