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Updated: Jan 8, 2026

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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百岁老人中与AD相关的血生物标志物:与认知和神经病理学的联系

Linda M C Lorenz1,2,3, Susan K Rohde1,2,3,4, Maruelle C Luimes1,2,3,4

  • 1Genomics of Neurodegenerative Diseases and Aging, Department of Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 19, 2025
PubMed
概括

像粉样β (Aβ),神经丝光 (NfL) 和状纤维酸蛋白 (GFAP) 这样的等离子体生物标志物可以在百岁老人中检测出早期的认知衰退和神经病理. 然而,化陶氏181 (pTau-181) 主要表明神经病理的晚期.

关键词:
老化的老化 衰老的老化粉样蛋白-β-β 的存在.基于血液的生物标志物一百岁以上的人.认知表现 认知表现状纤维化酸性蛋白质是状纤维化的.神经纤维光的光源是神经纤维光.酸化的 tau 181 是一种死亡后的神经病理学知道的 知道的 知道的

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