2018-2019年DEPICT (进入紧急儿科重症监护和运输期间护理的差异) 研究中的儿童和家长结果:12个月后续数据
Emma C Alexander1,2, Anjalika Mallick1, Sarah E Seaton3
1Paediatric Intensive Care Unit, St Mary's Hospital, London, United Kingdom.
概括
在儿童重症监护室 (PICU) 入院一年后,患有并发症的儿童的生活质量明显降低. 父母还报告了焦虑,抑郁和创伤后应激障碍 (PTSD) 的高率.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 儿童健康的结果.
- 家长的心理健康
背景情况:
- 在DEPICT研究之前评估了英国的紧急儿科重症监护和运输.
- 进行了12个月的随访,以评估长期结果.
研究的目的:
- 在儿童重症监护室 (PICU) 入院12个月后,评估儿童的生活质量和父母心理健康 (焦虑,抑郁,PTSD).
- 识别与受损结果相关的因素.
主要方法:
- 2020年对DEPICT队列 (n=419) 和他们的父母/照顾者进行的后续调查问卷.
- 评估儿科生活质量 (PedsQL),健康公用事业指数 (HUI-2) 和家长心理健康查.
- 分析基线特征,并发症和医疗保健利用情况.
主要成果:
- 与以前健康的儿童相比,12个月后,患有基线并发症的儿童的PedsQL和HUI-2得分明显较差.
- 大约30.9%的家长对焦虑呈阳性查,21.8%的抑郁,28.2%的创伤后应激障碍.
- 父母心理健康问题与儿童生活质量得分较差相关.
结论:
- 入住PICU的儿童可能会经历持续的生活质量损害,特别是那些有先前存在的疾病的儿童.
- 在PICU入院后观察到父母焦虑,抑郁和PTSD的高率.
- 需要进一步研究儿童和家庭支持以及最佳后续护理模式.
相关概念视频
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Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
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Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
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