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葡萄球菌肠毒素A 形成单细胞转录和巨细胞极化:感染和炎症中免疫反应的影响

Claudia Arasa1, Khaleda Rahman Qazi1, David Brodin2

  • 1Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.

European journal of immunology
|December 19, 2025
PubMed
概括

葡萄球菌肠毒素A (SEA) 改变单细胞如何分化为巨细胞 (MDM) 和树突细胞 (moDC). SEA-primed MDM促进高炎症T细胞反应,而moDC保留了抗原呈现功能.

关键词:
葡萄球菌肠毒素是葡萄球菌肠毒素.免疫激活系统的激活巨细胞的两极分化它们是超级抗原.

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