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Updated: Jan 8, 2026

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells
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Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells

Published on: January 18, 2017

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一种共价的全分子可以抑制NRF2依赖的癌症生长

Nilotpal Roy1, Tine Wyseure1, I-Chung Lo2

  • 1Vividion Therapeutics (United States) San Diego United States.

Cancer discovery
|December 19, 2025
PubMed
概括

一种名为VVD-065的新药通过促进NRF2的降解来向NRF2通路. 这种NRF2抑制剂在减少瘤生长和增加对癌症疗法的敏感性方面表现有前途.

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