在患有多发性硬化症的个体中,有或没有血流限制的抵抗运动后的疼痛反应
Christopher E Proppe1, Sean M Lubiak2, Paola M Rivera3
1Department of Human Performance Studies, Wichita State University, 1845 Fairmount St, Wichita, KS, 67260, USA. Christopher.proppe@wichita.edu.
European journal of applied physiology
|December 19, 2025
概括
低负荷抵抗运动与血流限制 (BFR) 有效地降低了多发性硬化症 (MS) 患者的疼痛敏感性. 这种方法可能为MS患者的疼痛管理提供一种有效的,较低负载的替代方案.
科学领域:
- 神经学 神经学
- 运动生理学 运动生理学
- 康复科学 康复科学 康复科学
背景情况:
- 疼痛是患有多发性硬化症 (MS) 的人群中普遍存在的,经常使人衰弱的症状.
- 运动诱导的缺痛症 (EIH),运动后疼痛敏感度的降低,通常需要高强度的抵抗训练.
- 血液流量限制 (BFR) 训练为实现EIH提供了一个潜在的低负载替代方案.
研究的目的:
- 在被诊断患有多发性硬化症的个体中研究EIH对具有BFR和没有BFR的抵抗运动的反应.
- 为了比较高负荷抵抗运动,低负荷抵抗运动与BFR (LL+BFR) 以及低负荷抵抗运动单独对疼痛敏感性的影响.
主要方法:
- 15名患有多发性硬化症的参与者进行了三次不同的运动:高负荷 (70% 1RM),LL+BFR (30% 1RM与BFR),低负荷 (30% 1RM没有BFR).
- 腿部延伸运动是单方面进行的.
- 运动前和运动后测量了直骨肌的疼痛压力值和耐受性;运动期间的疼痛评级被收集用于调解分析.
主要成果:
- 与高负荷和低负荷运动相比,LL+BFR导致疼痛压力值显著增加.
- 与低负荷运动相比,在LL+BFR后,疼痛压力耐受性显著更高.
- 虽然在运动期间的峰值疼痛在LL+BFR条件下更高,但它并没有调解过敏反应.
结论:
- 低负荷阻力运动与血液流量限制 (LL+BFR) 结合,有效地引起了MS患者的局部运动诱导性低痛性反应 (EIH).
- 与传统的高负荷和低负荷阻力运动相比,LL+BFR表现出更大的减痛效应.
- 在MS患者中,LL+BFR代表了一种有前途且强效的运动干预措施,用于急性调节MS患者的疼痛敏感性.
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