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肝硬度测量对预测肝硬度的作用部分肝切除术后的长期肝功能

Jiayao Huang¹, Lu Yao¹, Qingyu Wu¹

¹First Affiliated Hospital of Sun Yat-sen University, No. 58, Zhongshan Road Ⅱ, Yuexiu District, Guangzhou, China.

Abdominal radiology (New York)

|December 19, 2025

概括

肝癌和乙型肝炎患者的肝功能可能在手术后三个月稳定下来. 术前的指标如2D-SWE和ALBI得分可以预测康复.

科学领域:

肝病学肝病学是一种肝病学.
手术瘤学手术瘤学
医疗成像医学成像

背景情况:

部分肝切除术是慢性乙型肝炎 (CHB) 患者肝细胞癌 (HCC) 的常见治疗方法.
评估术后肝功能恢复对于患者的治疗结果至关重要.
术后指标可能为预测肝功能恢复提供见解.

研究的目的:

为了评估肝功能变化,在治疗初学者HCC和CHB患者的肝切除术后长达12个月.
探索术前指标的预测价值,包括二维剪切波弹性图 (2D-SWE),用于肝功能恢复.

主要方法:

预计将招募253名患者,随访1年.
在手术前和手术后的多个时间点收集数据 (第5天,第1,3,6,12个月).
用ROC曲线分析肝功能和逻辑回归的白蛋白-白素 (ALBI) 评分分析,用于预测因素分析.

主要成果:

通过ALBI评分测量的肝功能,最初恶化,然后在术后3个月稳定下来.
在61.3%的患者中观察到肝功能恢复.
恢复的预测因素包括较少的病变,较低的手术前2D-SWE值,较低的手术前ALBI得分,以及没有肝切除术后肝功能衰竭 (PHLF).

结论:

在CHB患者的HCC部分肝切除术后,肝功能恢复可能会在手术后的第三个月稳定.
手术前的2D-SWE,ALBI得分,病变数和PHLF是肝功能恢复的重要预测因素.

关键词:

专蛋白 - 胆氨基分数得分慢性乙型肝炎慢性乙型肝炎肝细胞癌是肝细胞癌.肝功能肝功能肝功能剪切波弹性图形学剪切波弹性图形学

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