饮食模式和乳腺癌风险:摩洛哥妇女的大规模病例控制研究
Najoua Lamchabbek1,2, Najia Mane3, Siham Mrah4
1Mohammed VI International School of Public Health, Mohammed VI University of Sciences and Health, Casablanca, Morocco. nlamchabbek@um6ss.ma.
European journal of nutrition
|December 19, 2025
概括
富含精制碳水化合物的饮食增加了乳腺癌的风险,而以植物为基础的地中海饮食显示了保护性的好处. 这项研究探讨了摩洛哥妇女的饮食模式和乳腺癌 (BC).
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 乳腺癌 (BC) 是全球女性的主要癌症.
- 饮食因素与BC风险有关,但证据不一致.
- 在摩洛哥,关于饮食和BC的研究是有限的.
研究的目的:
- 研究摩洛哥妇女饮食模式与乳腺癌 (BC) 风险之间的关联.
- 解决摩洛哥人口中饮食因素和BC研究的短缺问题.
主要方法:
- 一项涉及2800名摩洛哥妇女的病例控制研究.
- 使用主要成分分析 (PCA) 识别的饮食模式,基于经过验证的食物频率问卷 (FFQ) 的数据.
- 多变量逻辑回归计算了饮食模式四分位数中BC风险的几率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 确定了四种饮食模式.
- "糖和精制碳水化合物饮食"显示与BC风险有显著的积极关联 (OR = 7.71).
- "植物性和地中海饮食"表明与BC风险有显著的反向关联 (OR = 0.26).
- 富含乳制品的饮食显示出复杂的关联,最高四分位数与风险增加有关 (OR = 1.79).
- 对于富含动物蛋白质的饮食,没有发现显著的关联.
结论:
- 富含精制碳水化合物的饮食可能会增加乳腺癌的风险.
- 植物性和地中海饮食模式似乎可以提供对乳腺癌的保护性益处.
- 侧重于增加植物性和地中海食品摄入量的饮食干预措施可能对摩洛哥妇女的BC预防有益.
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