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Updated: Jan 8, 2026

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发现一种向人类GMP合成酶的小分子抑制剂

Zhiyan Wang1,2, Rajamanikandan Sundarraj2, Boao Mao2

  • 1Department of Molecular Pharmacology, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, 300060, China.

Molecular diversity
|December 19, 2025
PubMed
概括

研究人员发现了G18,一种新的小分子抑制剂,用于抑制瓜诺辛单酸合成酶 (GMPS). 这种化合物有效地抑制GMPS活性,抑制癌细胞的增殖,显示出抗癌药物开发的前景.

关键词:
这是一种抗癌药物.G18 G18 是一个很大的问题.关诺辛单酸盐合成酶 (GMPS) 是一种分子点是分子点.基于结构的虚拟选.

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