三个同时使用的rtCGM系统在1型糖尿病成年人身体活跃的周末营地周围的性能:一个前性的实验室和现实世界的研究
Sabrina Sanfilippo1,2, Ulrike Thurm2, Mats Renfordt2
1Exercise Physiology, Training & Training Therapy Research Group, Department of Human Movement Sciences, Sport, and Health, University of Graz, Graz, Austria.
Diabetes, obesity & metabolism
|December 19, 2025
概括
德克斯康G7和FreeStyle Libre 3实时连续血糖监测器 (rtCGM) 在1型糖尿病管理中表现出高准确性. 在这项比较研究中,Simplera rtCGM系统的准确性显著降低.
科学领域:
- 内分泌学 在内分泌学.
- 糖尿病 技术 技术
- 临床研究 临床研究
背景情况:
- 实时持续血糖监测 (rtCGM) 对于1型糖尿病 (T1D) 的管理至关重要.
- 在体力活动和运动引起的葡萄糖波动期间,rtCGM的准确性可能会受到损害.
- 精确的葡萄糖监测对于预防糖尿病并发症至关重要.
研究的目的:
- 为了比较三种rtCGM系统的准确性:Dexcom G7,FreeStyle Libre 3和Simplera.
- 在葡萄糖变化期间评估T1D患者的rtCGM性能.
- 确定用于糖尿病管理的不同rtCGM设备的临床实用性.
主要方法:
- 20名患有T1D的成年人参加了为期3天的实验室阶段,包括运动会和为期4天的家庭阶段.
- 参与者同时佩戴了德克斯康G7,FreeStyle Libre3和Simplera rtCGM设备.
- 通过将传感器葡萄糖值与复制毛细血管血糖测量结果进行比较,使用中位数绝对相对差异 (MedARD) 来评估rtCGM的准确性.
主要成果:
- 德克斯科姆G7 (MedARD 8.4%) 和FreeStyle Libre 3 (MedARD 7.5%) 的准确性和高精度可以比较.
- 与Dexcom G7和FreeStyle Libre 3 (p < 0.0001) 相比,Simplera rtCGM的准确性显著降低 (MedARD 13.8%),而 FreeStyle Libre 3 的准确性则明显降低 (p < 0.0001).
- 在Dexcom G7和FreeStyle Libre 3 (p = 0.35) 之间没有观察到显著的精度差异.
结论:
- 德克斯康G7和FreeStyle Libre 3rtCGM系统为T1D患者提供了高准确度.
- 辛普莱拉rtCGM系统的准确性较低,可能会影响其在临床实践中的可靠性.
- 这些发现支持使用高精度的rtCGM设备来优化T1D管理,特别是在体力活动期间.
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