运动干预对非糖尿病人群24小时连续葡萄糖概况的影响:系统性审查和元分析
Bingqing Yang1, Fenghua Sun2, Eric Tsz-Chun Poon3
1Department of Physical Education, Peking University, Beijing, China.
Diabetes, obesity & metabolism
|December 19, 2025
概括
运动在非糖尿病患者的血糖控制中提供了轻微的改善,降低了平均血糖 (MBG) 和平均血糖外游幅度 (MAGE). 需要进一步的研究来证实这些微妙的生理适应的临床相关性.
科学领域:
- 代谢健康 代谢健康
- 运动生理学 运动生理学
- 血糖控制 血糖控制 血糖控制
背景情况:
- 新出现的证据将血糖的变化与非糖尿病人的代谢健康联系起来.
- 持续葡萄糖监测 (CGM) 提供了对24小时葡萄糖概况的洞察力.
研究的目的:
- 评估运动对非糖尿病人群24小时连续葡萄糖概况的影响.
- 在运动干预后对关键的血糖变化指标进行元分析.
主要方法:
- 来自PubMed,科学网络,Embase和CNKI的研究的PRISMA指导的元分析,截至2025年8月.
- 分析了24小时平均血糖 (MBG),血糖外流的平均幅度 (MAGE),血糖峰值 (MAX),葡萄糖曲线下的4-6小时增量面积 (iAUC) 和范围内的时间 (TIR).
- 使用RoB2和ROBINS-I V2评估偏差风险;根据人口,年龄,研究设计和运动类型进行分组分析.
主要成果:
- 包括23项研究 (18项RCT,5项非RCT;408名参与者).
- 与对照组相比,运动显著降低了MBG,MAGE,MAX和4-6小时的IAUC,同时增加了TIR.
- 亚组分析显示年龄影响MBG,人口/运动类型影响MAGE.
结论:
- 急性炼显示了非糖尿病人的CGM指标的参数特定,尽管很小,但有所改善.
- 这些发现表明微妙的生理适应运动.
- 为了确定临床相关性,需要进行更大,更长时间和更好控制的试验.
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