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Updated: Jan 8, 2026

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.
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Published on: March 25, 2020

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乳酸糖调节人类皮肤纤维细胞中TGF-β1和IL-1β诱导的转录程序:对伤口管理的潜在影响

Gregory Thomas1, Kaysie L Banton, David Acuna

  • 1From the Trauma Research LLC (G.T., D.B.-O.); Trauma and Surgery Services, Swedish Medical Center, Englewood, Colorado (K.L.B., D.B.-O.); Trauma and Surgery Services, South Texas Health System-McAllen, McAllen, Texas (D.A., D.B.-O.); Trauma and Surgery Services, Wesley Medical Center, Wichita, Kansas (C.H.P., D.B.-O.); Trauma and Surgery Services, Intermountain Health Lutheran Hospital, Wheat Ridge (C.Z.-m., D.B.-O.); and Rocky Vista University, Parker, Colorado (D.B.-O.).

The journal of trauma and acute care surgery
|December 19, 2025
PubMed
概括

高乳酸水平可以通过改变纤维细胞基因表达和促进免疫抑制来损害伤口愈合. 代谢重编程和基因组修饰为减轻组织损伤提供了潜在的治疗点.

关键词:
乳酸盐是一种乳酸盐.代谢重编程是指代谢重编程.蛋白质的乳糖化 蛋白质的乳糖化转录性重编程是一种转录性重编程.伤口愈合 伤口愈合

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