肠道内镜后的食道状细胞癌侵入肌肉粘膜或粘膜下层:一个案例系列
Ippei Tanaka1, Boldbaatar Gantuya1, Kei Ushikubo1
1Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.
概括
高风险食道状细胞癌 (ESCC) 患者需要集中监测. 早期发现更深层的病变,特别是宫食道的病变,对于有效的内镜治疗和预防复发至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 内镜检查是指内镜检查.
背景情况:
- 食道状细胞癌 (ESCC) 的监测旨在早期检测.
- 患有多个Lugol-voiding病变的高风险患者需要谨慎监测.
- 尽管进行定期监测,但可以检测到晚期早期ESCC (pT1a-MM或更深).
研究的目的:
- 为了确定ESCC的临床病理特征.
- 为了确定监控期间在pT1a-MM或更深层次阶段检测到的ESCC的特征.
- 为高风险ESCC患者提供有针对性的监测策略.
主要方法:
- 早期ESCC治疗内镜切除的回顾性病例系列 (2015年1月 - 2024年10月).
- 纳入标准:ESCC高风险,每年或更短的监测间隔,pT1a-MM或更深的病变.
- 分析病变的位置,大小,深度和患者的结果.
主要成果:
- 五名男性患者 (平均年龄68岁) 符合标准.
- 在先前内镜检测后6-12个月检测到的病变.
- 宫食道 (Ce) 中有3个病变,中部 (Mt) 有1个,胸腔食道 (Lt) 下部有1个;前壁有Mt/Lt病变.
- 四个病变pT1a-MM,一个Ce病变pT1b-SM2与血管入侵;接受了化疗和放射治疗.
- 在任何病人身上都没有观察到癌症复发.
结论:
- 在ESCC监视期间,宫食道和中/下胸食道的前壁需要更多的注意.
- 这些发现可以提高ESCC高风险患者的监视内镜质量.
- 早期检测和内镜切除先进早期ESCC是有效的.
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