在青少年和成年人脊柱肌肉缩的温度诱导的症状
Leandra Aa Ros1, Lina M Vermeer1, Boudewijn Thm Sleutjes1
1Department of Neurology, University Medical Center Utrecht, UMC Utrecht Brain Center, Utrecht University, Utrecht, the Netherlands.
感冒,衰弱的恶化,在脊柱肌肉缩 (SMA) 患者中很常见,特别是那些症状严重的人. 了解冷症的机制可能会改善运动功能治疗.
科学领域:
- 神经学 神经学
- 临床研究 临床研究
- 患者的治疗结果.
背景情况:
- 温度敏感性会加剧神经肌肉疾病中的弱点.
- 在5q脊柱肌肉缩 (SMA) 中调查温度诱导的症状至关重要.
研究的目的:
- 确定SMA患者温度诱导症状的患病率,频率和严重程度.
- 为了比较SMA患者与健康和疾病对照对温度敏感性.
主要方法:
- 一项纵向队列研究使用标准化问卷评估了温度诱导的症状.
- 患有SMA类型1-4的患者和对照人群在基线和一年后被评估.
- 包括以前没有接受过治疗的患者,以隔离疾病特异性影响.
主要成果:
- 87%的SMA患者报告了感冒引起的症状,主要是感冒 (加重的虚弱).
- 在非健行性SMA患者中,感冒化更为普遍,并且与较低的RULM得分有关.
- 在疾病修饰治疗一年后,感冒的患病率保持不变.
结论:
- 感冒是SMA的常见症状,特别是在那些有更大的弱点的人中.
- 了解寒冷除机制可以为保护运动功能的新症状治疗提供信息.
- 需要进一步研究SMA中感冒症的治疗方法.
更多相关视频
08:16Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
Published on: March 4, 2014
09:18Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
Published on: January 12, 2019
相关概念视频
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
Increased Body Temperature
Decreased Body Temperature
Assessing Body Temperature - Axilla
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
