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Updated: Jan 8, 2026

Xenopus laevis as a Model to Identify Translation Impairment
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Xenopus laevis as a Model to Identify Translation Impairment

Published on: September 27, 2015

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无转移的酸化对于抑制被编程的-1核糖体框架转移是很重要的

Yueli Zhang1,2,3,4, Zhijian Li1,2,3,4, Huihui Chong1,2,3,4

  • 1NHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Science advances
|December 19, 2025
PubMed
概括

无转移蛋白 (SFL) 抑制了被编程的-1 核糖体框架转移 (-1 PRF) 和病毒活性. 它的结构和高酸化循环对于RNA结合和抗病毒功效至关重要,由特定的激酶调节.

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