[由于慢性病导致的副次性偏甲状腺症的棕色瘤:临床案例]
Laura Marisol Contreras-Vargas1, Mónica Sánchez-Cuevas2, Yatziri Haro-Sandoval1
1Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatría No. 48. Dirección de Educación e Investigación en Salud. León, Guanajuato, México.
Revista medica del Instituto Mexicano del Seguro Social
|December 19, 2025
概括
棕色瘤在患有慢性脏病 (CKD) 的青少年中罕见,可以表现为下病变. 早期诊断和治疗二次性甲状腺功能障碍症对于管理这些侵袭性骨瘤至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 腎臟病學 (nephrology) 是一種醫學.
- 口腔和牙面部外科手术
背景情况:
- 棕色瘤是与二次性副甲状腺功能障碍症相关的骨解病变.
- 它们影响了1.5-1.7%的患有二次性甲状腺功能障碍症的患者.
- 这些瘤很少见,作为儿科患者的初始临床表现.
研究的目的:
- 报告一个不寻常的棕色瘤病例,发生在患有V期慢性脏病 (CKD) 的青少年身上.
- 突出考虑棕色瘤在CKD患者呈现巨细胞病变的重要性.
主要方法:
- 一个14岁的女性患有5期CKD的病例报告.
- 临床检查,下部的计算机断层扫描 (CT) 和活检.
- 活检证实了巨细胞颗粒瘤; 二次性甲状腺功能障碍症和亚临床性甲状腺功能障碍症被诊断出来.
主要成果:
- 患者呈现出3厘米下棕色瘤,导致面部不对称.
- 扫描显示了局部攻击性病变,皮质扩张和软组织扩张.
- 二次性甲状腺功能障碍症的药物管理导致了充分的瘤反应.
结论:
- 棕色瘤是罕见的,作为儿童二级甲状腺功能障碍症的第一个临床症状.
- 在CKD患者中的巨细胞瘤需要对棕色瘤进行调查.
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