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基于应用程序的肌肉功能疗法,以改善中度阻断性睡眠呼吸暂停的部推进装置的坚持和结果:多中心随机试验协议

Juan Antonio Ibañez-Rodríguez^1,2, Carlos O'Connor-Reina^2,3, Ricardo Lucas⁴

¹Department of Medical Specialties and Public Health, Universidad Rey Juan Carlos, Madrid, Spain.

JMIR research protocols

|December 19, 2025

概括

这项研究调查了肌功能疗法 (MT) 的移动应用程序是否可以改善中度阻塞性睡眠呼吸暂停 (OSA) 患者使用下推进装置 (MAD) 的坚持和结果. 结果将确定基于应用程序的MT是否可以提高MAD治疗的有效性.

科学领域:

睡眠医学睡眠医学
呼吸系统医学呼吸系统医学
数字健康数字健康

背景情况:

部推进装置 (MADs) 是中度阻塞性睡眠呼吸暂停 (OSA) 的替代方案,但面临着坚持和长期挑战.
肌功能疗法 (MT) 显示出改善上呼吸道肌肉度和减少OSA严重性的前景.
作为MAD治疗OSA的辅助剂,MT的作用需要进一步研究.

研究的目的:

评估基于应用程序的MT程序 (气道健身房) 是否改善了中度OSA患者对MAD治疗的坚持.
评估基于应用程序的MT对使用MAD的中度OSA患者的临床结果和睡眠参数的影响.

主要方法:

一个多中心,前性,随机化,受控试验,涉及18-75岁的成年人中等程度的OSA (呼吸暂停-呼吸暂停指数15-30).
参与者被随机分为四组:安慰剂,仅MT,仅MAD和MAD加MT.
结果包括呼吸暂停-呼吸暂停指数,氧气不和指数,睡眠质量和舌头强度的变化,通过远程医疗和睡眠日记监测遵守.

主要成果:

招聘开始于2024年2月,数据收集计划到2025年12月.
该协议于2025年1月进行了审查,概述了研究程序.
完整的研究结果正在等待最终分析.

结论:

本协议详细介绍了一项随机试验,评估基于应用程序的MT作为中度OSA的MAD治疗的辅助.
该研究旨在提供证据,证明将数字MT与MAD集成的有效性,以改善OSA管理.

关键词:

我已经开始工作了.爱荷华州的口腔表演乐器坚持性坚持性气道体育馆的体育馆数字健康数字健康下巴的推进装置设备.肌功能神经功能疗法阻塞性睡眠呼吸暂停症是什么睡眠质量睡眠质量远程医疗远程医疗

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