在瘤病患者群体中扩散性异常性骨架度:对1053名患者的横截面分析
Shahriar Kolahi1, Madjid Shakiba2, Shahryar Rahmani2
1Musculoskeletal Imaging Research Center (MIRC), Department of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran; Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Department of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Seminars in arthritis and rheumatism
|December 19, 2025
概括
扩散性异常性骨架强症 (DISH) 在癌症患者中很常见,影响超过30%. 这种以带骨化为特征的疾病在老年男性和特定癌症类型中更为普遍,这表明共享的疾病途径.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 类风湿病学 类风湿病学
背景情况:
- 扩散性异常性骨高静止症 (DISH) 是一种由带骨化标志着的全身性疾病.
- 有限的数据存在于DISH在瘤病患者的流行.
研究的目的:
- 确定DISH和早期DISH在新诊断的癌症患者中的患病率和分布.
- 评估DISH与患者人口统计,癌症类型和并发症之间的关联.
主要方法:
- 对1053名瘤学患者进行了回顾性横截面研究.
- 使用已确定的放射学标准评估DISH的胸腔腹腔皮层CT扫描.
- 测量脊椎体密度和记录脊外肠病变的记录.
主要成果:
- 在30.3%的患者中存在DISH (13.8%确立,16.5%早期阶段).
- 在老年男性和患有,胃和结直肠癌的患者中观察到更高的患病率.
- DISH与脊椎骨密度下降和频繁的脊外肠病相关.
结论:
- 在瘤学患者中,DISH是一种常见的发现,通常与脊外肠道病变和骨密度下降共存.
- DISH和恶性瘤之间可能存在共享的致病机制.
- 需要进一步的研究来探索DISH和癌症之间的关系.
相关概念视频
Bone Disorders
5.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.0K
Osteoclasts in Bone Remodeling
3.8K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.8K
Disorders of the Skeletal Muscle
1.7K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
1.7K
Radiological Investigation III: Pulmonary Angiogram and PET Scan
385
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
385


