在性虐待主义中,皮层网络内的灰质增加
Carla L Harenski1, Fadwa Cazala1, J Michael Maurer1
1The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA.
Journal of psychiatric research
|December 19, 2025
概括
这项研究表明,性虐待主义者在特定的部区域,包括关节 (TPJ) 中表现出增加的灰质体积. 这些发现将大脑结构的差异与性虐待主义联系起来.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 法医心理学 法医心理学
背景情况:
- 性虐待是一种严重的偏爱症,但其神经生物学基础在很大程度上是未知的.
- 以前的研究集中在心理和法医方面,忽视了大脑结构的相关性.
研究的目的:
- 调查与性虐待相关的神经网络和特定的大脑区域.
- 探索灰质体积与性虐待的严重程度之间的关系.
主要方法:
- 从232名被监禁男性获得结构性MRI扫描,其中包括116名性犯罪者.
- 性虐待力度表 (SeSaS) 评估了罪犯的虐待力严重程度.
- 多变量 (基于源的形态学 - SBM) 和单变量 (基于声素的形态学 - VBM) 的分析发现了灰色物质体积差异.
主要成果:
- 无论是SBM还是VBM,都确定了SeSaS得分和后部区域之间的关联,特别是关节 (TPJ) 和状.
- 与对照和低撒迪主义个体相比,具有较高SeSaS分数的个体在这些时间区域中显示出增加的灰质体积.
- 在这项研究中发现的右TPJ区域与之前的功能性MRI研究中涉及的性虐待和疼痛处理的区域重叠.
结论:
- 这些发现提供了多模式的证据,将时皮层网络与性撒迪主义联系起来.
- 在TPJ和状回形中增加的灰质体积可能代表性虐待的神经相关性.
相关概念视频
Sex-linked Disorders
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Aggression
Humans engage in aggression when they seek to cause harm or pain to another person. Aggression takes two forms depending on one’s motives: hostile or instrumental. Hostile aggression is motivated by feelings of anger with intent to cause pain; a fight in a bar with a stranger is an example of hostile aggression. In contrast, instrumental aggression is motivated by achieving a goal and does not necessarily involve intent to cause pain (Berkowitz, 1993); a contract killer who murders for hire...
Bullying
A modern form of aggression is bullying. As you learn in your study of child development, socializing and playing with other children is beneficial for children’s psychological development. However, as you may have experienced as a child, not all play behavior has positive outcomes. Some children are aggressive and want to play roughly. Other children are selfish and do not want to share toys. One form of negative social interactions among children that has become a national concern is bullying.
Maturation of Endosomes
The early endosome containing internalized molecules matures through transformations in its location, morphology, intraluminal pH, and membrane protein composition. Together, these changes result in a more acidic late endosome that contains multiple intraluminal vesicles; therefore, the late endosome is also called a multivesicular body (MVB).
Changes in location
The maturing endosome moves along microtubules from the periphery of the cell towards the perinuclear region. This movement of the...
Changes in location
The maturing endosome moves along microtubules from the periphery of the cell towards the perinuclear region. This movement of the...
Abnormal Proliferation
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Necrosis
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become anucleated and die, but their...
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become anucleated and die, but their...


