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Updated: Jan 7, 2026

Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
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病原性podocin变体在贩运,膜组织和降解途径上表现出明显的缺陷

Pei-Chen Lu1, Ruth Rollason2, Chia-An Chou3

  • 1Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, United Kingdom; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung, Taiwan.

European journal of cell biology
|December 19, 2025
PubMed
概括

在NPHS2的致病变体导致脏综合征通过破坏podocin蛋白的稳定性和贩运. R138Q变体通过与ER相关的途径降解,影响功能.

关键词:
基因突变是一种基因突变.遗传性疾病是一种遗传性疾病.脏 - 脏 - 脏脏病综合征 - 脏病综合征波多西尼是一种葡萄酒.

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