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在间歇性肺部疾病中,卧式和倾斜CT之间的量化差异

Hyungin Park¹, Ji-Yeon Han², Jinwook Baek²

¹Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81, Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

Clinical imaging

|December 19, 2025

概括

倾向性计算机断层扫描 (CT) 显示了间歇性肺病 (ILD) 评估的高可重现性,与卧底CT相比. 在先进或地面玻璃不透明度占主导地位的ILD的纵向研究中建议谨慎.

科学领域:

放射学和成像学放射学和成像学
肺部医学肺部医学
医学诊断医学诊断医学诊断

背景情况:

间歇性肺病 (ILD) 的评估通常依赖于计算机断层扫描 (CT).
定量CT (QCT) 提供了对肺部异常的客观测量.
对QCT可重复性来说,评估卧姿和卧姿成像之间的测量变异性至关重要.

研究的目的:

为了比较ILD患者的倾斜QCT与卧卧QCT的测量变异性和可重复性.
评估QCT测量与不同位置的肺功能测试 (PFT) 参数的相关性.
为了确定影响QCT测量的位置间变异性的因素.

主要方法:

从277名ILD患者 (2021年1月至2023年12月) 进行对联卧底和倾斜CT扫描的回顾性分析.
使用深度学习软件量化肺部异常;通过布兰德-阿尔特曼和类内相关系数 (ICC) 评估的可变性.
使用Pearson的相关性和Steiger的Z测试评估与PFT的相关性;回归分析确定了可变性预测因素.

主要成果:

卧式和卧式QCT之间的高可重现性 (ICC>0.75) 与低变异性 (约. 2%用于纤维化,4%用于ILD总程度).
地面玻璃不透明度 (GGO) 显示出最高的变化,特别是在广泛的疾病中.
倾向于蜂的蜂显示出更强的PFT相关性;过敏性肺炎与更大的总ILD变异性相关.

结论:

倾向于QCT显示高可重现性和可比的PFT相关性与卧床QCT.
易受CT是可靠的单一时间点ILD评估.
纵向比较需要谨慎在先进或GGO主导的ILD由于潜在的变化.

关键词:

间歇性肺病间歇性肺病在俯卧的位置.定量计算断层扫描 (QCT) 是一种定量计算断层扫描.可复制性可复制性

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