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探索欧洲美利诺羊的气候适应:一个景观基因组学方法

M Di Civita¹, P Wiener², M Marr²

¹Department of Agriculture Environment and Food Science, University of Molise, Campobasso 86100, Italy.

Animal : an international journal of animal bioscience

|December 19, 2025

概括

全球气候变化需要了解牲畜的遗传适应. 这项研究确定了与温度和降水等环境因素相关的欧洲美利诺羊的遗传标记,揭示了适应的关键基因.

科学领域:

基因组学就是基因组学.
环境科学环境科学
动物科学动物科学

背景情况:

畜牧业适应气候变化至关重要.
绵羊 (Ovis aries),特别是美利诺品种,是研究本地适应的理想模型,因为它们的全球分布和多样化的特征.
了解绵羊适应的遗传基础对于可持续的羊毛生产和牲畜管理至关重要.

研究的目的:

研究欧洲美利诺羊种群的景观基因组学.
确定单核酸多态 (SNP) 和生物气候变量之间的遗传关联.
发现参与绵羊环境适应的基因和基因组区域.

主要方法:

通过使用5000个SNP芯片数据 (38381个SNP,736只动物) 对24个欧洲美利诺羊种群的基因组分析.
使用BayPass软件对基因型数据和19个生物气候变量进行关联分析.
基因本体学丰富分析以确定功能途径和候选基因.

主要成果:

检测到168个异常SNP和232个相关基因.
同热度 (温度变化) 显示出最重要的基因组关联.
1号和14号染色体上的基因组区域表现出极端的贝叶斯因子,确定了STAT1,COL11A1和COL6A3等关键基因.

结论:

该研究确定了特定的基因组区域和基因,这些基因可能会推动美利诺羊的环境适应.
研究结果表明,已识别的基因在温度调节,毛囊发育和适应不同气候中的作用.
这项研究提供了对全球重要畜牧品种适应性基因架构的洞察.

关键词:

通过BayPass,通过BayPass.适应气候变化适应气候变化基因型与环境的关联温度变化的可变性世界气候气候

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