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Updated: Jan 8, 2026

In vitro Assembly of Semi-artificial Molecular Machine and its Use for Detection of DNA Damage
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Published on: January 11, 2012

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SARM1作为dSDNA检测器来感知核损伤和病毒驱动细胞死亡

Adel Avetisyan1, Ernesto Manzo1, Marc R Freeman1

  • 1Vollum Institute, OHSU, Portland, OR, USA.

Molecular cell
|December 19, 2025
PubMed
概括

酶SARM1,一种NAD+酶,可以与双链DNA (dsDNA) 结合. 这一发现表明SARM1可能在检测DNA损伤和启动细胞死亡途径方面发挥作用.

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