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Updated: Jan 8, 2026

Single Myofiber Culture Assay for the Assessment of Adult Muscle Stem Cell Functionality Ex Vivo
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Single Myofiber Culture Assay for the Assessment of Adult Muscle Stem Cell Functionality Ex Vivo

Published on: February 15, 2021

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在肌肉干细胞激活过程中,Numb的RBFOX2-依赖的替代拼接调节了Notch信号传递

Kangning Lin1, Jing Liu1, Erin H Y Tse1

  • 1Division of Life Science, Center for Stem Cell Research, HKUST-Nan Fung Life Sciences Joint Laboratory, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Center for Neurodegenerative Diseases, InnoHK, Hong Kong, China; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.

Stem cell reports
|December 19, 2025
PubMed
概括

卫星细胞 (SCs) 在激活时迅速改变替代拼接 (AS),这对于肌肉再生至关重要. RBFOX2调节这个AS,影响SC激活和Notch信号通路.

关键词:
没有口,没有口.一个麻木的麻木.在Rbfox2中使用Rbfox2.替代性拼接是一种替代性的拼接.肌肉干细胞是肌肉的干细胞.干细胞激活活动干细胞激活

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