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模拟人类多能干细胞衍生的肝脏器官中的免疫系共同发展.

Milad Rezvani1, Susanna Quach2, Kyle Lewis3

  • 1Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Department of Pediatric Gastroenterology, Nephrology and Metabolic Medicine, Augustenburger Platz 1, 13353 Berlin, Germany; Berlin Institute of Health (BIH) at Charité-Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT)Augustenburger Platz 1, 13353 Berlin, Germany; Berlin Institute of Health, BIH Charité Clinician Scientist Program, 10178 Berlin, Germany; Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Der Simulierte Mensch (Si-M), Joint research center of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Amrumer Str. 33, 13353 Berlin.

Journal of hepatology
|December 19, 2025
PubMed
概括

人类胎儿肝脏类器官 (FLOs) 成功模拟肝脏发育和免疫细胞共同发育. 这种突破性的有机体系统可以研究肝损伤和潜在的再生疗法.

关键词:
胎儿的肝脏 胎儿的肝脏血液形成 血液形成 血液形成人类多能干细胞是人类多能干细胞.豁免权是一种豁免权.肝脏器官类型的器官骨髓发育 (Myelopoiesis) 是一种形成骨髓的过程.这些是iPSCs.

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