与季节性流感相比,COVID-19的30天死亡风险增加
Won Suk Choi1, Kyoung-Hoon Kim2, Dong-Sook Kim2
1Division of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Republic of Korea.
概括
在韩国,COVID-19患者的30天死亡率明显高于流感患者. 这种风险在各种患者群体中升高,突出显示需要继续预防和接种COVID-19疫苗的努力.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 季节性流感和COVID-19是严重的公共卫生问题.
- 了解比较死亡风险对于资源分配和公共卫生战略至关重要.
研究的目的:
- 为了比较韩国COVID-19和季节性流感患者之间的30天全因死亡率.
- 为了确定不同死亡风险的子组.
主要方法:
- 全国范围,基于人口的队列研究,利用国家医疗保险索赔数据库 (2022年7月 - 2023年12月).
- 分析包括12802169例COVID-19病例和2888777例流感病例.
- 对人口和临床因素进行调整后勤回归,以比较30天全因死亡率.
主要成果:
- 与流感相比,COVID-19与30天全因死亡率显著增加有关 (aOR: 1.76;95%CI: 1.60-1.94).
- 跨年龄,性别,医疗保健利用率和并发症子组观察到高的COVID-19死亡风险.
- 在18-64岁的成年人 (aOR:2.93),住院患者 (aOR:2.55) 和心肌梗塞患者 (aOR:2.24) 中发现风险更高.
结论:
- COVID-19的短期死亡风险远远高于流感,即使在流行后的时代.
- 调查结果强调了COVID-19预防策略的持续重要性,包括疫苗接种.
- 这是后COVID-19时代第一个大规模的亚洲全国性研究,比较了这两种呼吸系统疾病.
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