患有子宫内膜异位症的女性的焦虑和抑郁症:在生育环境中进行的一项比较研究
Bourdon Mathilde1, Bolac Laure2, Cervantes Celie3
1Université de Paris, Faculté de Médecine, Paris, France; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital universitaire Paris Centre (HUPC), Department of Gynecology Obstetrics and Reproductive Medicine, Centre Hospitalier Universitaire (CHU) Cochin, Paris, France; Department 3I « Infection, Immunité et inflammation", Institut Cochin, INSERM U1016.
Fertility and sterility
|December 19, 2025
概括
与没有子宫内膜异位症的女性相比,接受体外受精 (IVF) 的子宫内膜异位症妇女的抑郁率较高. 这凸显了在子宫内膜异位症患者的辅助生殖技术治疗期间需要综合心理支持的需要.
科学领域:
- 生殖医学 生殖医学
- 精神病学是一个精神病学.
- 妇科 妇科 妇科 妇科
背景情况:
- 子宫内膜异位症影响生育年龄的女性,并与不孕不育和疼痛有关.
- 对于患有子宫内膜异位症的女性来说,辅助生殖技术 (ART) 如IVF/ICSI和生育保护 (FP) 是常见的.
- 子宫内膜异位症和ART对心理健康的心理影响,特别是焦虑和抑郁症,需要进一步调查.
研究的目的:
- 为了确定患有子宫内膜异位症的女性进行卵巢刺激和卵细胞检索的焦虑和抑郁症的患病率.
- 为了将这些患病率与没有子宫内膜异位症的女性进行类似手术进行比较.
- 确定与患有子宫内膜异位症的女性焦虑和抑郁相关的因素.
主要方法:
- 在一所大学医院进行了一项观察性队列研究.
- 参与者包括接受IVF/ICSI或生育保护 (FP) 的妇女.
- 通过成像 (TVS/MRI) 确定子宫内膜异位状态,并在卵细胞检索日使用医院焦虑和抑郁量表 (HADS) 评估焦虑/抑郁.
主要成果:
- 患有子宫内膜异位症的IVF/ICSI患者 (5.5%) 与对照组 (0.8%) 的抑郁症发生频率明显高.
- 在子宫内膜异位症患者中,焦虑的患病率较高,但没有统计学意义.
- 严重的深度失联症与焦虑和/或抑郁症独立相关 (aOR 2.7).
结论:
- 接受试管婴儿/ICSI治疗的子宫内膜异位症妇女患有抑郁症的患病率更高.
- 在生育保存人群中,没有发现焦虑或抑郁的显著差异.
- 对于子宫内膜异位症患者,尤其是严重疼痛患者,将心理支持纳入ART至关重要.
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