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相关概念视频

Bone Remodeling01:40

Bone Remodeling

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Gross Anatomy of Bone01:17

Gross Anatomy of Bone

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The two main features of a long bone are the diaphysis and the epiphysis.
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in...
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相关实验视频

Updated: Jan 8, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
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实践更新:骨和软组织病理学的新兴实体

Nooshin K Dashti1, Scott E Kilpatrick2

  • 1Department of Pathology and Laboratory Medicine Dartmouth Health, 03766, Lebanon, NH, USA; Geisel School of Medicine at Dartmouth, 03766, Lebanon, NH, USA.

Human pathology
|December 19, 2025
PubMed
概括

最近分子工具的进步已经完善了骨和软组织瘤的分类. 本综述强调了五种新发现的瘤实体,具有显著的预后和治疗影响.

关键词:
贝塔-catenin 的使用情况.在 NFAT NFAT 中.这就是NUT-sarcoma.伪内分泌肉瘤是一种伪内分泌肉瘤.拉布多米索尔科马 (Rhabdomyosarcoma) 是一种癌症.表面的神经瘤瘤是什么VGLL3VGLL3VGLL3VGLL3VGLL3VGLL3VGLL3VGLL3VGLL3VGLL3血管血管 血管血管是什么意思

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Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
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Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
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相关实验视频

Last Updated: Jan 8, 2026

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Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

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科学领域:

  • 在瘤学瘤学.
  • 病理学 病理学 病理学
  • 分子生物学分子生物学

背景情况:

  • 我们对骨和软组织瘤的理解有了显著的进化.
  • 辅助测试,特别是分子工具,导致了新的瘤实体的出现和改进.
  • 识别新的瘤实体对于预后和治疗至关重要.

研究的目的:

  • 审查最近的骨和软组织瘤分类实践更新.
  • 讨论最近描述的五种瘤实体.
  • 突出这些新实体的预后和治疗相关性.

主要方法:

  • 对有关骨和软组织瘤的当前文献的综述.
  • 专注于通过先进的诊断技术识别的最近描述的实体.
  • 对形态和分子特征的讨论.

主要成果:

  • 讨论了最近描述的五种瘤实体:伪内分泌肉瘤,NUT重排的肉瘤,头的VGLL3重排的状细胞狂宫肉瘤,表面的神经结晶性FET::ETS融合瘤和NFATC1/2-重排的表皮状血管瘤.
  • 这些实体表现出不同的形态和分子特征.
  • 它们的认可具有显著的预后和治疗意义.

结论:

  • 骨和软组织瘤的分类是动态的,是由分子进步驱动的.
  • 准确识别新描述的瘤实体对于患者管理至关重要.
  • 持续的研究对于进一步完善瘤分类和治疗策略至关重要.