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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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通过cGAMP介导的保护性抗瘤免疫反应可以在没有LRRC8/VRAC通道的情况下进行

Fabian M B Thöne1, Maya M Polovitskaya2, Uta E Höpken3

  • 1Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin; Graduate program of the Freie Universität Berlin, Germany.

The Journal of biological chemistry
|December 19, 2025
PubMed
概括

体积调节的离子通道 (VRAC) 运输2'3'-cGAMP,这对于抗瘤免疫是至关重要的. 然而,这项研究发现瘤生长和免疫反应独立于小鼠的VRAC介导cGAMP运输.

关键词:
癌症生物学 癌症生物学在 SWELL1 中使用 SWELL1.这就是VSOR VSOR.适应性免疫反应是一种适应性免疫反应.细胞的增殖细胞的增殖.化物道化物道循环核化物循环核化物细胞因子 细胞因子这是先天免疫力.瘤免疫学 瘤免疫学

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