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Updated: Jan 8, 2026

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
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在Rhno1缺失的小鼠模型中的DNA损伤信号和细胞周期检查点的缺陷

Joonyoung Her1, Adithi Santhosh1, Yanira Gonzalez-Rodriguez1

  • 1Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.

Cell death discovery
|December 19, 2025
PubMed
概括

RHNO1蛋白对于DNA修复和细胞循环检查点在DNA损伤的反应中至关重要. 在B细胞中RHNO1的损失会损害分离过程中的DNA修复,但在正常情况下不会影响B细胞的生长.

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