治疗方法,微生物学发现和内眼炎患者的视力敏度之间的关联:一项回顾性多中心研究
Shayaan Kaleem1, Andrew Mihalache1, Amir-Ali Golrokhian-Sani2
1Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Eye (London, England)
|December 19, 2025
概括
最初的治疗方法和微生物学发现没有影响内眼炎患者的视力敏度结果. 然而,与培养负病例相比,细菌病例的再处理率较高.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 视网膜外科手术 视网膜外科手术
背景情况:
- 眼内膜炎是一种严重的眼内感染,可能导致视力丧失.
- 迅速有效的治疗对于视力恢复至关重要.
- 了解初始治疗和致病剂对视觉结果的影响对于临床管理至关重要.
研究的目的:
- 为了确定初始治疗方法 (点击和注射 vs. 帕斯普拉纳视切除术) 与微生物学发现在治疗后的视力敏度之间的关联.
- 根据治疗方式和微生物学结果,比较视觉结果和再处理率.
主要方法:
- 在2011年至2023年期间治疗的111名内眼炎患者的回顾性研究.
- 在治疗后的1,3,6个月和12个月视力敏度 (VA) 的分析.
- 线性回归调整为年龄,性别,治疗时间和基线VA.
主要成果:
- 在任何时间点,细菌和培养负病例之间的VA改善没有显著差异.
- 在抽水和注射 (T / I) 和部分计划性视体切除 (PPV) 组之间,VA改善没有显著差异.
- 在细菌病例中观察到更高的再处理率 (56%) 与培养负病例相比 (22%).
结论:
- 最初的治疗方法 (T/I与PPV) 和微生物学 (细菌与培养负面) 并没有显著地影响endophthalmitis的视觉结果.
- 细菌性内炎病例与更高的重新治疗需求有关.
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