基于文献的肠道微生物群饮食指数及其与阻塞性睡眠呼吸暂停风险的关联:基于人口的横截面研究
Yuhan Dai1, Jukun Song2, Guohui Bai3,4
1School of Stomatology, Zunyi Medical University, Zunyi, China.
BMC nutrition
|December 20, 2025
概括
与肠道微生物群健康相关的饮食模式可能会降低阻塞性睡眠呼吸暂停 (OSA) 的风险. 这项研究发现,基于文献的肠道微生物群饮食指数 (LBDI-GM) 和OSA之间存在保护性关联,特别是在女性中.
科学领域:
- 营养科学 营养科学
- 微生物组研究 微生物组研究
- 睡眠医学 睡眠医学
背景情况:
- 关于基于文献的肠道微生物群饮食指数 (LBDI-GM) 和阻塞性睡眠呼吸暂停 (OSA) 之间的联系,研究有限.
- 调查这种关系对于了解潜在的饮食对OSA的影响至关重要.
研究的目的:
- 检查LBDI-GM与OSA之间的关联.
- 为了确定影响肠道微生物群的饮食模式是否会影响OSA风险.
主要方法:
- 2015-2018年国家健康和营养检查调查 (NHANES) 数据的横截面分析.
- 使用加权多变量后勤回归来评估LBDI-GM和OSA之间的关系.
- 通过自我报告问卷和基于与肠道微生物组特征相关的饮食模式的LBDI-GM来评估OSA.
主要成果:
- 总共分析了8707名参与者.
- 在对混因素进行调整后,LBDI-GM显示与OSA风险有显著的反向关联 (OR=0.967,p=0.025).
- 保护作用在女性参与者中更为明显.
结论:
- 确定了LBDI-GM和OSA之间的反向关联.
- 促进肠道微生物群健康的饮食模式可能有助于降低OSA风险.
- 这些发现表明,在OSA管理中,饮食干预的可能性很大.
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