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Updated: Jan 8, 2026

Author Spotlight: Purifying High-Quality Tubulin to Study Protein Dynamics and Therapeutic Applications
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作为图布林聚合抑制剂的林/皮里多-皮里米丁衍生物:设计,合成,计算和抗癌评估

Divyakshi Arya1, Gulshan Aara Khan1, Shweta Singh1

  • 1Department of Chemistry, D.D.U. Gorakhpur University, Gorakhpur, Uttar Pradesh, India.

Archiv der Pharmazie
|December 20, 2025
PubMed
概括

新的oline/pyrido[2,3-d]pyrimidin-4(3H) -one衍生物显示出具有选择性的抗癌潜力. 化合物4g对乳腺和结肠癌细胞表现出显著的氨酸抑制和抗增殖活性,具有有利的类似药物的特性.

关键词:
在 DFT 方面,它是最重要的.这是一种抗癌药物.这是一种抗增殖药物.分子对接的分子对接.奇诺林 / 皮里多 - 皮里米丁.氨酸的聚合活性活动.

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