患者参与药物开发的患者观点:一种定性研究
Fatima I Auwal1,2, Elizabeth J Clark1, Caroline S Copeland1
1Centre for Pharmaceutical Medicine Research, King's College London, London, UK.
Current medical research and opinion
|December 20, 2025
概括
患者参与药物开发的价值是改善试验和赋予患者权力. 有效的策略需要明确的沟通,包容性和公平的补偿,以实现可持续的,有意义的参与.
科学领域:
- 制药科学 制药科学
- 医疗保健服务研究 医疗服务研究
- 患者倡导 患者倡导
背景情况:
- 患者参与 (PE) 在药物开发中至关重要,但从患者的角度来看,对其价值的经验证据有限.
- 现有的文献强调了诸如赋权和改进的试验设计之类的好处,以及沟通,真实性和可持续性的挑战.
研究的目的:
- 探索有效的患者参与药物开发的感知价值,挑战和战略.
- 收集患者,护理人员和参与制药行业的患者倡导者的见解.
主要方法:
- 使用在线进行的半结构面试进行的定性研究.
- 参与者是通过专业网络招募的,他们有健康状况,照顾或倡导方面的经验.
- 通过反射主题分析分析了22次采访的数据.
主要成果:
- 参与改善临床试验结果,个人赋权和社区支持.
- 关键的挑战包括结构性障碍,代币主义,缺乏反和不一致的做法.
- 有效的策略包括明确的沟通,包容性,能力建设和公平的报酬.
结论:
- 真正的,包容的,透明地沟通的患者参与是变革性的.
- 解决结构性不一致性和优先考虑关系而不是交易对于可持续的PE在医学发展至关重要.
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