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Updated: Jan 7, 2026

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E2F2通过调节NBR1介导的上皮-介质细胞过渡促进了喘性肺损伤和气道重塑

Long Zhao1, Xiaolan Shi1, Ning Wang1

  • 1Department of Respiratory and Asthma, Xi'an Children's Hospital, No.69, Xijuyuan Lane, Lianhu District, Xi'an, Shaanxi, 710003, China.

Naunyn-Schmiedeberg's archives of pharmacology
|December 20, 2025
PubMed
概括

E2F转录因子2 (E2F2) 通过通过NBR1-介导的表皮-介质细胞转换 (EMT) 途径驱动气道炎症和重塑来促进喘. 针对E2F2/NBR1轴为喘提供了一个潜在的治疗策略.

关键词:
气道改造 气道改造 气道改造喘 喘 是一种E2F2 E2F2 E2F2 E2F2 E2F2 E2F2在EMT中,EMT是EMT.NBR1 是一个国家标准.

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