以色列诺罗病毒的废水流行病学,2022年
Tal Maoz Atias1, Yaniv Lustig2, Enosh Tomer3
1Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
废水监测显示,以色列广泛传播诺罗病毒. 诺罗病毒的季节性因地区而异,受人口,温度和湿度的影响,挑战了"冬季病毒"的分类.
科学领域:
- 环境微生物学环境微生物学
- 公共卫生监督是对公共卫生的监督.
- 病毒学 病毒学
背景情况:
- 诺罗病毒在全球范围内引起显著的急性胃肠炎.
- 以色列缺乏常规的诺罗病毒监测.
- 基于废水的流行病学提供了一种新的监测方法.
研究的目的:
- 在以色列实施基于废水的全国性流行病学,以监测诺罗病毒.
- 为了监测诺罗病毒基因组I (GI) 和II (GII) 的循环.
- 分析影响诺罗病毒动态的地理和人口因素.
主要方法:
- 在2022年,以色列各地的13个地点每周抽取废水样本.
- 逆转录定量PCR用于诺罗病毒RNA检测.
- 使用线性混合效应模型与环境和人口学变量进行统计分析.
主要成果:
- 在超过95%的样本中检测到诺罗病毒RNA,表明持续循环.
- 观察到明显的季节性模式:GI在夏季达到顶峰,GII在春季.
- 确定了时间动态的区域差异.
- 病毒载量与人口和最低温度正相关;与湿度和社会经济指数负相关.
结论:
- 诺罗病毒的季节性因地区而异,并受环境和人口因素的影响.
- 将诺罗病毒仅归类为"冬季病毒"是一种过度简化.
- 废水监测为诺罗病毒流行病学提供了宝贵的见解.
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