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Updated: Jan 8, 2026

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
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Published on: October 4, 2019

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miRNA模块用于精确,可调节的基因表达控制

Rongrong Du1, Michael J Flynn1, Karan Mahe1

  • 1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA.

Molecular cell
|December 20, 2025
PubMed
概括

研究人员开发了基于miRNA的新型电路,称为DIMMERs,用于精确控制转基因表达. 这些调节器确保在不同基因剂量中均的蛋白质水平,推动基因疗法和生物技术研究.

关键词:
剂量补偿剂量补偿剂量补偿基因治疗的基因疗法这是一个微型RNA.多种规范性的法规.精确的基因表达控制.合成生物学 合成生物学

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