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综合性多组学揭示了微生物基因组变异,导致自闭症谱系障碍中的改变宿主微生物相互作用

Wanning Chen1, Xinjun Wang2, Ruixin Zhu3

  • 1Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Clinical and Translation Research Center, Shanghai First Maternity and Infant Hospital, School of Life Sciences and Technology, Tongji University, Shanghai 200092, P.R. China; Institutes of Biomedical Sciences, School of Life Sciences, Inner Mongolia University, Hohhot 010070, P.R. China.

Cell reports. Medicine
|December 20, 2025
PubMed
概括

肠道中的微生物基因组变异与自闭症谱系障碍 (ASD) 有关. 分析1100多名儿童的遗传差异和代谢物,为ASD提供了新的诊断见解.

关键词:
自闭症谱系障碍 自闭症谱系障碍基因组变异的基因组变异调解分析 调解分析代谢生物组的代谢生物组微生物组是一个微生物组.

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