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微生物衍生的免疫刺激小分子增强了肺癌中的抗PD-1疗法

Rachel C Newsome1, Huijia Liu1, Bright Agbodzi2

  • 1Department of Medicine, University of Florida College of Medicine, Gainesville, FL, USA.

Cell reports. Medicine
|December 20, 2025
PubMed
概括

细菌类细菌产生一种化合物,cis-Bac429,通过促进CD8+ T细胞反应来增强抗PD-1癌症治疗. 这一发现为治疗抗PD-1-耐火性非小细胞肺癌提供了新的途径.

关键词:
免疫检查点抑制抑制免疫检查点抑制免疫疗法 免疫疗法微生物组是一个微生物组.非小细胞肺癌的肺癌.

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