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认知偏差对解释进行修改 缓解了nocebo过敏症
Tessa Rooney1, Louise Sharpe1, Jemma Todd1
1School of Psychology, The University of Sydney, Australia.
The journal of pain
|December 20, 2025
概括
修改对疼痛的解释偏见增加了nocebo过敏症,由疼痛预期调解. 减少与疼痛相关的解释可能针对临床环境中的nocebo疼痛减轻.
科学领域:
- 心理学 心理学 心理学
- 疼痛科学 疼痛科学
- 认知神经科学 认知神经科学
背景情况:
- 解释偏差,即倾向于将模两可的刺激解释为与疼痛相关的倾向,与疼痛严重程度相关.
- 了解nocebo过敏症的机制对于开发有效的疼痛管理策略至关重要.
研究的目的:
- 为了调查认知偏差修改对解释 (CBM-I) 是否影响nocebo过敏症.
- 确定疼痛预期在解释偏差和nocebo过敏症之间关系中的调解作用.
主要方法:
- 参与者被随机分配到CBM-I针对疼痛相关或良性解释.
- 一个nocebo诱导程序涉及假的皮肤间电神经刺激 (TENS) 与热疼痛相结合.
- 通过在相同的热刺激下比较TENS和无TENS试验中的疼痛评级来评估nocebo过敏症.
主要成果:
- 可靠地观察到nocebo过敏症,并通过疼痛预期进行调解.
- CBM-I成功操纵了解释偏差,疼痛偏差组显示出更强的偏差.
- 接受疼痛重点CBM-I的参与者与良性重点组相比,表现出显著更大的nocebo过敏症.
结论:
- 针对疼痛相关解释的认知偏差修改放大了nocebo过敏症.
- 解释偏差通过增加疼痛预期在nocebo过敏症中起因作用.
- 通过CBM-I减少与疼痛相关的解释偏见,为临床疼痛管理提供了潜在的心理干预.
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