遗传参数估计和精细绘制的牛奶生产特征和体细胞得分在中国simmental牛
Chunxiao Dong1, Peipei Ma2, Yongjie Tang3
1College of Animal Science and Technology, Ningxia University, Yinchuan 750021, China; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Journal of dairy science
|December 20, 2025
概括
这项研究揭示了影响中国西蒙特牛牛奶产量的关键遗传因素. 识别这些基因位置有助于开发基因组选择策略,以提高双重用途品种的乳制品性能.
科学领域:
- 动物遗传学动物遗传学
- 乳制品科学 乳制品科学
- 量化遗传学 量化遗传学
背景情况:
- 中国西蒙特牛是可持续农业的重要双重用途品种.
- 这种品种在温带条件下的牛奶特征的遗传基础尚不清楚.
研究的目的:
- 估计9种牛奶生产特征的遗传参数.
- 确定与这些特征相关的基因组位点在中国simmental牛.
主要方法:
- 利用了17556个测试日记录和1788头牛的全基因组测序数据.
- 使用随机回归测试日模型与莱根德多项式.
- 进行了全基因组关联和贝叶斯微绘分析.
主要成果:
- 牛奶特征的遗传概率估计在0.09到0.52之间.
- 在已知基因 (BOP1,MROH1,NEGR1) 和新兴关联 (CACNB4,MTHFD2L,SGMS1) 附近确定了重要的SNP.
- 遗传相关性在哺乳期内有所变化,在牛奶中相邻的日子 (DIM) 之间最强.
结论:
- 更好地了解牛奶生产特征的遗传调节.
- 提供了在双重用途的牛养殖计划中对基因组选择的实际目标.
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