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Updated: May 13, 2026

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由丁诺波纳毒素M-PONTX-Dq4e衍生的tcGAPDH基抑制剂,具有三酸性作用

Emanuel Paula Magalhães1, Dânya Bandeira Lima1, Evelline Araújo Edson2

  • 1Postgraduate Programm on Pharmaceutical Sciences, Federal University of Ceará, Brazil.

Toxicon : official journal of the International Society on Toxinology
|December 20, 2025
PubMed
概括

来自M-PONTX-Dq4e的新型体对Trypanosoma cruzi表现出强烈的tripanocidal活性,为Chagas提供了一个对benznidazole的有希望的替代品.

关键词:
抗微生物是一种抗微生物.查加斯病是查加斯病的一种疾病.丁诺波纳毒素是一种毒素.有理性的药物设计.这就是TcGAPDH.

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